Use one change at a time
Keep the original manufacturer profile, record each test, and save a new profile only after the result is repeatable.
Choose the closest symptom and your filament. The tool starts with safe checks before suggesting slicer changes, so you do not change five settings at once.
Most first-layer failures come from plate contamination, an incorrect plate/profile choice, or calibration—not from the model.
Keep the original manufacturer profile, record each test, and save a new profile only after the result is repeatable.
Turn the printer off and follow its manufacturer documentation if you see damaged wiring, smoke, severe grinding, or a hotend collision you cannot clear safely.